“心理突破”
用英语怎么说？

In human trials, zalsupindole demonstrated favorable safety profiles and elicited significant clinical improvements in patients with major depression, without inducing subjective sensory alterations. However, prominent neuroscientists remain skeptical, arguing that the psychological breakthroughs and mystical states generated during a trip are fundamental to genuine emotional healing. They assert that cognitive shifts, rather than mere physical dendrite growth, drive lasting recovery. Despite this skepticism, major pharmaceutical companies are investing billions in neuroplastogens, recognizing their immense market potential and convenience. Classic psychedelics require highly supervised, resource-intensive settings to mitigate risks, which limits their accessibility. Conversely, non-hallucinogenic neuroplastogens could easily integrate into standard psychiatric care, offering home-based treatments devoid of cultural baggage. Whether the subjective trip is essential to efficacy remains an open scientific question, but neuroplastogens are poised to redefine the future of neuropsychopharmacology.

在人类临床试验中，zalsupindole表现出了良好的安全性，并使重度抑郁症患者获得了显著的临床改善，且未诱发主观感觉改变。然而，杰出的神经科学家们仍持怀疑态度，他们认为在幻觉体验中产生的心理突破和神秘状态对于真正的情感治愈至关重要。他们断言，认知转变而非单纯的物理树突生长才是持久康复的动力。尽管存在这种怀疑，大型制药公司正向神经塑料原投入数十亿美元，看好其巨大的市场潜力和便利性。传统的幻觉剂需要高度监管且资源密集型的环境来降低风险，这限制了它们普及。相反，非致幻性神经塑料原可以轻易融入常规精神科护理中，提供无需承担文化包袱的居家治疗。主观的幻觉体验对疗效至关重要还是一个悬而未决的科学问题，但神经塑料原势必将重新定义神经精神药理学的未来。